Histamine, Skin Itching and Urticaria

Home/Histamine, Skin Itching and Urticaria

Histamine can cause both skin itching, eczema and hives of the skin.

Histamine can cause problems in the body in 3 ways. Biochemically the histamine involving mechanisms that are going on within the body, are different.

1)  Firstly histamine is released from the mast cells of the body during a “true” allergy. Histamine is released in
high amounts when the body sees an invader (for Itchy skin can be controlled with topical products and internal treatment of the skin condition.example a food it doesn’t like). A true allergy occurs following ingestion of a certain food or after coming in contact with allergen. This usually occurs within 2 to 4 hours of contact.

2) A Food Intolerance. This is different between a ‘true allergy’ and a food intolerance. The symptoms that are experienced with a food intolerance occur much slower than with a true allergy i.e. 12 to 72 hours after contact with a substance. A food intolerance can be linked to Leaky Gut Syndrome.

3) A histamine intolerance is different again and involves a type of food intolerance that involves foods that are rich in histamine. An intolerance is usually related to low levels of enzymes that are responsible for the binding and metabolization of histamine.

These enzymes are diamine oxidase (DAO) and histamine-N-methyltransferase (HNMT).  As a result of this enzyme deficiency, histamine can build up in the body causing not only skin problems but also such things as migraine headache, digestive problems such as gut ache or diarrhoea or flushing. More serious reactions such as an anaphylactic response can occur, quickly and without warning.

The following foods stimulate histamine production

If you have already eradicated the most common allergy foods (see Diet information) but are still experiencing itching, consider eradicating or keeping the below histamine rich roods to a minimum.REDUCE HISTAMINE RICH FOODS



Avoid all alcohol as it can interfere with the production of diamine oxidase, an enzyme involved in the metabolism of histamine.

Calcium, Histamine and Allergies

A low calcium level can be associated with an increase in histamine levels.

Excessive intake of the following foods can decrease calcium absorption and utilization thereby contributing to a histamine-type allergic reaction when consumed.

It is recommended that you have a Hair Tissue Mineral Analysis performed to determine if you have a problem with calcium. Calcium is a complicated mineral and having adequate calcium levels is not as simple as taking a supplement – it is very much about the balance of minerals.

Also be aware that drinking milk or consuming dairy products will not assist greatly, if at all. Milk is a poorly absorbed source of calcium and is related to other health concerns such as elevated growth hormone and raised blood sugar levels.

If your calcium levels are low, it is advisable to REDUCE THE FOLLOWING FOODS:

  • Whole wheat, cereals, oatmeal
  • sodium and soft water
  • colas (soft drinks)
  • turnip greens, spinach and chard.